William H. Gray III 30th Street Station is the third busiest train station in the nation, with 53,000 travelers a day. SEPTA’s Regional Rail Lines go to neighborhoods throughout Philadelphia and the suburbs, all the way to Delaware and New Jersey, and to Philadelphia International Airport. New Jersey Transit trains cross the Delaware River, and AMTRAK trains travel to destinations as far away as Miami, Chicago, and New Orleans.


Penn Medicine Station is a Regional Rail Station located in University City. It is served by the Airport Line, Warminster Line, Wilmington/Newark Line, West Trenton Line, and Media/Elwyn Line as well as Bus Routes 12 and 40. Opened in 1995, it is ideally located for those travelling to Penn Medicine, University of Penn, and Drexel University.


SEPTA recommends using a SEPTA Key card to obtain best value. SEPTA Key is a reloadable, contactless chip card that offers a host of options for seamless travel and the self-serve flexibility of loading/reloading SEPTA fares to match your travel needs. Fare Kiosks can be found in all Broad Street and Market-Frankford Line Stations, at Bus Loops, at Center City Regional Rail Stations (Temple University, Jefferson Station, Suburban Station, 30th Street Station and Penn Medicine Station) and at the Airport. Kiosks accept cash, credit, debit, tokens, Apple Pay, Google Pay, & Samsung Pay. Best part – you can reload your SEPTA Key online at SEPTAKey.org.


University City itself is one of the most easily traversed areas of Philadelphia. SEPTA offers trolleys [Routes 10, 11, 13, 34, and 36], buses [21, 42, and 49], and the Market-Frankford Line servicing the neighborhood from end to end. University City also boasts some of the most bicycle-friendly streets in the area, with a network of roughly 25 miles of bike lanes.


For those who prefer to drive, car services Zip Car and Enterprise CarShare offer numerous vehicles on loan. With two interstate highways converging by the Schuylkill River, drivers have excellent access to the regional highway system.